LYVE1 ELISA Kit for Human(Homo sapiens) | EIAab.comLYVE1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > LYVE1(Gene name) > Human

LYVE1 (Gene name),

Lymphatic vessel endothelial hyaluronic acid receptor 1 (Protein name ), LYVE1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

LYVE1(UNQ230/PRO263;CRSBP1;HAR;XLKD1);

Protein name:

Lymphatic vessel endothelial hyaluronic acid receptor 1(LYVE-1);

Alternative:

Extracellular link domain-containing protein 1;Cell surface retention sequence-binding protein 1(CRSBP-1);Hyaluronic acid receptor;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer; disulfide-linked. Interacts with PDGFB and IGFBP3. Forms a transient ternary complex with PDGFB and PDGFRB in TGN.

Function:

Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Subcellular Location:

Membrane Single-pass type I membrane protein Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface.

Protein Attributes:

Sequence length:

322

Sequence:

50:

100:

150:

200:

250:

300:

322:

DKNPEESKSP | SKTTVRCLEA | EV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000256178

Pfam:

PF00193

SMR:

Q9Y5Y7

String:

Q9Y5Y7

UniGene:

Hs.655332

KEGG:

hsa:10894

MIM:

605702

Uniprot:

Q9Y5Y7

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ELISA Kit for Human LYVE-1

Cat.:

E13600m

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96T

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ELISA Kit for Human LYVE-1

Cat.:

E13600h

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96T

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ELISA Kit for Human LYVE-1

Cat.:

E13600b

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Packing:

96T

CLIA Kit for Human LYVE-1

Cat.:

U13600m

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MSDS:

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Packing:

96T

CLIA Kit for Human LYVE-1

Cat.:

U13600h

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MSDS:

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Packing:

96T

CLIA Kit for Human LYVE-1

Cat.:

U13600b

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human LYVE-1

Cat.:

P13600Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human LYVE-1

Cat.:

P13600Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human LYVE-1

Monoclonal Antibody for Human LYVE-1

Protein for Human LYVE-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"LYVE-1, a new homologue of the CD44 glycoprotein is a lymph-specific receptor for hyaluronan."
Banerji S. , Ni J. , Wang S.-X. , Clasper S. , Su J. , Tammi R. , Jones M. , Jackson D.G.
J. Cell Biol.144:789-801(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
2.

"HAR: a novel homolog of CD44 and putative hyaluronic acid receptor encoded by a gene on human chromosome 11p15."
Winkelmann J.C. , Basu S. , Ozdemir E. , Blough R.I.
Submitted (1999-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ARG-116
tissue: Liver.
5.

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-53
tissue: Plasma.
6.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-53
tissue: Liver.

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